Studies on the Components of Fruits of Melia azedarach L. var. japonica MAKINO
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چکیده
منابع مشابه
The Toxicity and Anti-cancer Activity of the Hexane Layer of Melia azedarach L. var. japonica Makino’s Bark Extract
In this study, the 4-week oral toxicity and anti-cancer activity of the hexane layer of Melia azedarach L. var. japonica Makino's bark extract were investigated. We carried out a hollow fiber (HF) assay and 28- day repeated toxicity study to confirm the anti-cancer effect and safety of the hexane layer. The HF assay was carried out using an A549 human adenocarcinoma cell via intraperitoneal (IP...
متن کاملCytotoxic tirucallane triterpenoids from Melia azedarach fruits.
The phytochemical investigation of the dichloromethane-soluble part of the methanol extract obtained from the fruits of Melia azedarach afforded one new tirucallane-type triterpene, 3-alpha-tigloylmelianol and three known tirucallanes, melianone, 21-beta-acetoxy-melianone, and methyl kulonate. The structure of the isolated compounds was mainly determined by 1D and 2D NMR experiments as well as ...
متن کاملFatty Acid Composition and Toxicity of Melia azedarach L. Fruits against Malaria Vector Anopheles stephensi
The fruit of Melia azedarach L. (Meliaceae) was extracted with hexane, and its fatty acids methyl ester was analyzed using GC/MS. Thirteen components representing 85.1% of the total extract were identified. The major components identified were methyl palmitate (18.8%), methyl linolenate (16.1%) and methyl linoleate (9.8%). The fruits’ extract had a LC50 of 5.5 ppm agai...
متن کاملAn antiviral meliacarpin from leaves of Melia azedarach L.
Bioassay guided purification of the ethyl acetate extract of leaves of Melia azedarach led to the isolation of the limonoid 1-cinnamoyl-3,11-dihydroxymeliacarpin, which showed IC50 values of 6 microM and 20 microM for vesicular stomatitis (VSV) and herpes simplex (HSV-1) viruses, respectively. Its structure was established by spectroscopic methods.
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1970
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.90.1_99